Protein Principles for Diabetes
Dietary considerations can present a Hobson's choice in diabetes. Even when the intake is nutritious, assimilating it can be another matter. Then there is the problem of progression of diabetic complications if one ends up with excess glucose or fat in the system. Excess carbohydrates in a meal, and the resulting uncontrolled blood sugar levels can be detrimental to any number of tissues, from the lens of the eye, to the neurons, small blood vessels and the kidneys. Fat is also a problem with increase incidences of atherosclerosis, large vessel disease and cardiac complications. What, then is the appropriate macronutrient for the diabetic population? Enough medical literature exists to suggest that in diabetes, proteins are probably the best bet.
Proteins are the natural choice of the body when faced with diabetes. In uncontrolled diabetes, muscle protein is broken down into amino acids to be converted into glucose by the liver. If left to fend for itself, this can create a commotion within the body. Since proteins have to supply enough energy to substitute for carbohydrates, proteins are broken down faster than they are made. The body ends up with a protein deficit, a situation with subtle, yet far-reaching effects on normal body functions. Importantly, for diabetics, a protein deficit has been shown to impair resistance to infections (Ganong WF). Replenishing the depleting protein stores is a vital requirement of all diabetic diets.
Importance of proteins in a diabetic has been well documented. The American Associations of Clinical Endocrinologists have made it clear that not much evidence exists to indicate that the patients with diabetes need to reduce their intake of dietary proteins. The AACE recommends that 10-20% of the calorie intake in diabetes should come from proteins (AACE Diabetes Guidelines). It is in fact believed that this is one nutrient that does not increase blood glucose levels in both diabetics and healthy subjects (Gannon et al).
Nutrition therapy for diabetes has progressed from prevention of obesity or weight gain to improving insulin's effectiveness and contributing to improved metabolic control (Franz MJ). In this new role, a high protein diet (30% of total food energy) forms a very pertinent part of nutrition therapy. One of the most important causes for type II diabetes is obesity. Excess body fat raises insulin resistance and higher levels of insulin are required to bring down blood sugars as the weight increases (Ganong WF). Another problem with excess fat is the clogging of arteries with atherosclerotic plaques that is responsible for a wide range of diabetic complications. Any mechanism that reduces body fat decreases insulin resistance and improves blood glucose control. Parker et al have also shown that a high protein diet decreased abdominal and total fat mass in women with type II diabetes. Other studies by Gannon et al. and Nuttall et al have verified that blood glucose levels and glycosylated hemoglobin (a marker of long term diabetic control) reduce after 5 weeks on a diet containing 30% of the total food energy in the form of proteins and low carbohydrate content. It is speculated that a high protein diet has a favorable effect in diabetes due to the ability of proteins and amino acids to stimulate insulin release from the pancreas. Thus, a high protein diet is not only safe in diabetes, but can also be therapeutic, resulting in improved glycemic control, and decreased risk of complications related to diabetes.
The benefits of a high protein diet do not end here. Individual protein components of such a diet, when aptly chosen, can have other advantages as well. Dietary supplements containing proteins like whey and casein come highly recommended. Casein is a milk protein and has the ability to form a gel or clot in the stomach. The ability to form this clot makes it very efficient in nutrient supply. The clot is able to provide a sustained, slow release of amino acids into the blood stream, sometimes lasting for several hours (Boirie et al. 1997). A slow sustained release of nutrients matches well with the limited amount of insulin that can be produced by the pancreas in diabetes. A protein supplement containing casein can thus increase the amount of energy assimilated from every meal and, at the same time, reduce the need for pharmacological interventions to control blood sugar.
Whey proteins and caseins also contain "casokinins" and "lactokinins', (FitzGerald) which have been found to decrease both systolic and diastolic blood pressure in hypertensive humans (Seppo). In addition, whey protein forms bioactive amine in the gut that promotes immunity. Whey protein contains an ample supply of the amino acid cysteine. Cysteine appears to enhance glutathione levels, which has been shown to have strong antioxidant properties -- antioxidants mop up free radicals that induce cell death and play a role in aging.
Thus, development of a protein supplement containing casein and whey can provide an apt high protein diet and its health benefits to individuals suffering from diabetes, obesity and hypercholesterolemia.
Founded in 2001, Protica, Inc. is a nutritional research firm with offices in Lafayette Hill and Conshohocken, Pennsylvania. Protica manufactures capsulized foods, including Profect, a compact, hypoallergenic, ready-to-drink protein beverage containing zero carbohydrates and zero fat. Information on Protica is available at http://www.protica.com
You can also learn about Profect at http://www.profect.com
Copyright - Protica Research - http://www.protica.com
The American Association of Clinical Endocrinologists. Medical guidelines for the management of diabetes. AACE Diabetes Guidelines, Endocr Pract. 2002; 8(Suppl 1).
Boirie, Y., Dangin, M., Gachon, P., Vasson, M.P., Maubois, J.L. and Beaufrere, B. (1997) Slow and fast dietary proteins differently modulate postprandial protein accretion. Proclamations of National Academy of Sciences 94, 14930-14935.
Counous, G. Whey protein concentrates (WPC) and glutathione modulation in cancer treatment. Anticancer Research 2000; 20, 4785-4792
FitzGerald RJ, Murray BA, Walsh D J. Hypotensive Peptides from Milk Proteins. J. Nutr. 134: 980S-988S, 2004.
Franz MJ. Prioritizing diabetes nutrition recommendations based on evidence. Minerva Med. 2004; 95(2):115-23.
Gannon et al An increase in dietary protein improves the blood glucose response in persons with type 2 diabetes. Am J Clin Nutr 2003; 78:734- 41.
Gannon MC, Nuttall J A, Damberg G. Effect of protein ingestion on the glucose appearance rate in people with type II diabetes. J Clin Endocrinol Metab 86: 1040-1047, 2001
Ganong W F. Review of Medical Physiology, 21st Ed. Lange Publications 2003
Ha, E. and Zemel, M.B. Functional properties of whey, whey components, and essential amino acids: mechanisms underlying health benefits for active people. Journal of Nutritional Biochemistry 2003; 14, 251-258.
Kent KD, Harper WJ, Bomser JA. Effect of whey protein isolate on intracellular glutathione and oxidant-induced cell death in human prostate epithelial cells. Toxicol in Vitro. 2003; 17(1):27-33.
Nuttall et al. The Metabolic Response of Subjects with Type II Diabetes to a High-Protein, Weight-Maintenance. J Clin Endocrinol Metab 88: 3577-3583, 2003
Parker et al. Effect of a High-Protein, High-Monounsaturated Fat Weight Loss Diet on glycemic Control and Lipid Levels in Type 2 Diabetes. Diabetes Care 25:425-430, 2002.
Seppo, L., Jauhiainen, T., Poussa, T. & Korpela, R. () A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects. Am. J. Clin. Nutr. 2003; 77: 326-330.Unger RH. Glucagon physiology and pathophysiology. N Engl J Med. 1971; 285:443- 449.
Copyright 2004 - Protica Research - http://www.protica.com
This RSS feed URL is deprecated, please update. New URLs can be found in the footers at https://news.google.com/news
Float on | Type 2 diabetes comparable to barge traffic, benefits from catching it early - THV11.com KTHV
Women with pregnancy-related diabetes may be at risk for chronic kidney disease - National Institutes of Health (press release)
Exercising for Diabetes Sufferers
Exercise is often recommended in treating type 1 (insulin-dependent) and type 2 (noninsulin- dependent) diabetes ~ both as a stand-alone activity and in combination with diet and drug therapy. For people who are heavily dependent on medicines, exercise cannot replace drugs but it does contribute to normalizing the glucose metabolism.
Diabetic Neuropathy, a nerve disorder caused by diabetes, is characterized by a loss or reduction of sensation in the feet, and in some cases the hands, and pain and weakness in the feet. The symptoms of diabetic neuropathy vary.
Diabetic Complications - Can Benfotiamine Help Prevent Them?
Diabetic complications contribute too many life threatening diseases globally. The root cause of diabetic complications is elevated glucose levels which contribute to blood vessel damage.
Benfotiamine And Diabetic Retinopathy
Damage from diabetes can occur in different areas of the eye. It can occur to the cornea, nerves controlling the muscles of the eye, the lens, optic nerve and retina.
Diabetes Break-Thru Helps Battle Blood Sugar Woes
Are you a diabetic? If so, you are definitely not alone. Recent numbers report that there are some 18 million Type 2 diabetics.
Build Health: Want To Prevent Diabetes?
To prevent diabetes you will get a real jolt when you follow the prescription offered up in the "Journal of the American Medical Association."This 'prestigious' organization reported on separate studies of coffee drinkers in Sweden and Finland.
Diabetes Symptoms, Causes & Types
Diabetes affects the manner in which the body handles carbohydrates, fats and proteins. If neglected, diabetes can have serious complications.
Becoming a Diabetes Expert
I am a diabetes expert. No I'm not a doctor or a nurse.
Get More Out Of Life While Managing Your Diabetes
When I was first diagnosed with Type 1 Diabetes at the age of 21, I had not given the first thought to living a healthy diabetic lifestyle. As far as I was concerned, a healthy lifestyle was reserved only for fitness junkies and overweight moms.
Recognizing Early Symptoms Diabetes
Early symptoms diabetesStay alert in recognizing early symptoms of diabetes. Certain symptoms put you on notice and you'll want to decrease the chance of developing into complications.
If You Have Diabetes, You May Be Entitled To No Cost Diabetic Supplies
This article is intended to inform people with diabetes in regards to their diabetic supplies. When I found out that my sister was diagnosed with the disease I started to research more and came across some useful information that might be helpful to others.
Fibromyalgia and Insulin Resistance
Do you have symptoms that relate to an insulin imbalance? If you have fibromyalgia, look and see if you also have hypoglycemia, insulin resistance, or diabetes symptoms. These types of blood sugar imbalances can cause fibromyalgia pain to get worse.
Pre-Diabetes: Check Engine Warning Light
Your car has an early detection system and so does your body. Take 3 minutes to read this article and learn how you can save yourself a life time of aches, pains, and costly medical bills.
Do You Have Diabetes? Symptoms Of Diabetes And How To Address Them
Diabetes mellitus is a condition resulting from the pancreas' inability to produce enough insulin, which is needed by the body to help create energy. A deficiency of or ineffectiveness of insulin leads to high glucose levels in the blood, thus, leading to this illness.
Diabetes Awareness: Will They Recognize You?
Imagine how it feels to look younger, feel younger, and act younger! Now, think about how others see you. Are you ready to make a lasting impression on your friends and family? Great!Taking charge of your diabetes through exercise can give you a younger look and feel not to mention ?? a younger attitude!As you read this message, remember this: You don't pay the price to improve your health, you reap the benefits of being healthy!Treatment of diabetes has gone through dramatic changes in the past two decades.
Tools to Manage Your Diabetes
It's estimated that in the US, over 18 million people over the age of 20 have diabetes. If you happen to have been diagnosed with diabetes, make sure you're getting all the right diabetes treatment supplies.
Diabetic Frozen Shoulder. An Explanation of The Frozen Shoulder - Diabetes Connection?
Diabetic frozen shoulder is a major problem. The pain and limited function that it causes can seriously limit the normal activities of day-to-day life.
Insulin Resistance And Complex Carbohydrates
One of the biggest mistakes that weight loss failures make is cutting out carbs altogether. An example of this flawed ideology is the Atkins diet.
Diabetes Awareness: Diabetes on the Job
When you go to work, your diabetes goes with you.You get up, get showered, get breakfast, get to work.
Exercise - The Only Hope for Diabetes!
Why is it that the smallest paragraph in diabetes prevention magazines is about exercise? Exercise is probably the only hope for the diabetes crisis. If you have diabetes or some one in your family tree does, beware! You really have one choice, keep moving.
|home | site map|